Yes, a husband can borrow money against his wife home. In such cases, however, the wife must be a co-borrower because her property will be used as collateral for the loan. The creditworthiness of both the husband and wife will be evaluated by the bank or financial institution, and the loan amount will be determined based on their joint income and repayment capacity. Before applying for a home loan on a property owned by the spouse, it is best to consult with a financial expert.